The chemistry is identical with flooded cell batteries. Specifically Pb-PbO2-sulfuric acid. They are designed to be lighter weight as the original design was for aircraft batteries... of course when you put one together for automotive use you can then make it heavier...AGM stands for Absorbed Glass Mat. it is different than the lead plate lead acid batteries in chemistry and construction. Both types have their own place in useage.
Depends on the lithium chemistry. LiFePO4 is pretty much as safe as batteries get and in most cases are suitable as "drop in" replacements for lead-acid (if they have a built in BMS). The 4 cell version has a resting 100% charge voltage of 13.6V.I would make sure your home and auto insurance are up to date. Pay attention to your personal property coverage. Make sure everyone knows how to get out of the house and where to meet in case of fire.
Now buy that lithium battery and park it outside.
Are they interchangeable? I know they were not in the BMW F chassis (standard cars vs. M cars).AGM is just the "next step up" from old lead-acid batteries. They have less gassing/acid leakage, last longer, and resist cold temps better. They're not lighter. For example, consider the following three battery types, all size H7/Group 94R (Which is what the 2023 F-150 uses):
AGM: Optima Yellow-Top (60.5lbs), Odyssey (54.8lbs), Champion (54lbs)
Lead: Duralast Gold (42.9lbs), Champion (43lbs)
Lithium: PowerTex (16.5lbs), Antigravity (15.6lbs)
AGM's old tech these days. It's been around for decades at this point, and is well proven. You do need a different charger if you use AGM batteries. Aside from that, they pretty much just work.
Personally, if I were looking for a battery upgrade, I'd go with Lithium. That's what's in those "jump packs" you see people use, laptops, cell phones, etc. It's ultra-lightweight, doesn't lose charge over time, and many of the automotive applications have nifty built-in features such as "push a button when your battery is dead and start your car anyway". They're sure pricey though!